SERMs (selective estrogen receptor modulator), acting as estrogen receptor β agonists in hepatocellular carcinoma cells, inhibit the transforming growth factor-α-induced migration via specific inhibition of AKT signaling pathway

Selective estrogen receptor modulator (SERM) interacts with estrogen receptors and acts as both an agonist or an antagonist, depending on the target tissue. SERM is widely used as a safer hormone replacement therapeutic medicine for postmenopausal osteoporosis. Regarding hepatocellular carcinoma (HC...

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Detalles Bibliográficos
Autores principales: Matsushima-Nishiwaki, Rie, Yamada, Noriko, Hattori, Yuria, Hosokawa, Yui, Tachi, Junko, Hori, Takamitsu, Kozawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746762/
https://www.ncbi.nlm.nih.gov/pubmed/35007301
http://dx.doi.org/10.1371/journal.pone.0262485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746762/
https://www.ncbi.nlm.nih.gov/pubmed/35007301
http://dx.doi.org/10.1371/journal.pone.0262485

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