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c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

Polycystic kidney disease is an inherited degenerative disease in which the uriniferous tubules are replaced by expanding fluid-filled cysts that ultimately destroy organ function. Autosomal dominant polycystic kidney disease (ADPKD) is the most common form, afflicting approximately 1 in 1,000 peopl...

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Detalles Bibliográficos
Autores principales: Smith, Abigail O., Jonassen, Julie A., Preval, Kenley M., Davis, Roger J., Pazour, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746764/
https://www.ncbi.nlm.nih.gov/pubmed/34962918
http://dx.doi.org/10.1371/journal.pgen.1009711