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Evaluation of a novel combination of TRAM-34 and ascorbic acid for the treatment of corneal fibrosis in vivo

Corneal injury and aberrant wound healing commonly result in corneal fibrosis and subsequent vision loss. Intermediate-conductance calmodulin/calcium-activated K+ channels (K(Ca)3.1) have been shown to promote fibrosis in non-ocular and ocular tissues via upregulation of transforming growth factor b...

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Detalles Bibliográficos
Autores principales: Fuchs, Allison A., Balne, Praveen K., Giuliano, Elizabeth A., Sinha, Nishant R., Mohan, Rajiv R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746773/
https://www.ncbi.nlm.nih.gov/pubmed/35007294
http://dx.doi.org/10.1371/journal.pone.0262046