Intragenic proviral elements support transcription of defective HIV-1 proviruses

HIV-1 establishes a persistent proviral reservoir by integrating into the genome of infected host cells. Current antiretroviral treatments do not target this persistent population of proviruses which include latently infected cells that upon treatment interruption can be reactivated to contribute to...

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Detalles Bibliográficos
Autores principales: Kuniholm, Jeffrey, Armstrong, Elise, Bernabe, Brandy, Coote, Carolyn, Berenson, Anna, Patalano, Samantha D., Olson, Alex, He, Xianbao, Lin, Nina H., Fuxman Bass, Juan I., Henderson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746790/
https://www.ncbi.nlm.nih.gov/pubmed/34962974
http://dx.doi.org/10.1371/journal.ppat.1009982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746790/
https://www.ncbi.nlm.nih.gov/pubmed/34962974
http://dx.doi.org/10.1371/journal.ppat.1009982

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