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Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches

Background: Hepatocellular carcinoma (HCC) is one of the most widespread malignancies and is reported as the fourth most prevalent cause of cancer deaths worldwide. Therefore, we aimed to investigate the probable mechanistic cytotoxic effect of the promising 2-thioxoimidazolidin-4-one derivative on...

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Detalles Bibliográficos
Autores principales: Nafie, Mohamed S., Khodair, Ahmed I., Hassan, Hebat Allah Y., El-Fadeal, Noha M. Abd, Bogari, Hanin A., Elhady, Sameh S., Ahmed, Safwat A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746798/
https://www.ncbi.nlm.nih.gov/pubmed/35011314
http://dx.doi.org/10.3390/molecules27010083