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Roux-en-Y Gastric Bypass and Caloric Restriction but Not Gut Hormone-Based Treatments Profoundly Impact the Hypothalamic Transcriptome in Obese Rats

Background: The hypothalamus is an important brain region for the regulation of energy balance. Roux-en-Y gastric bypass (RYGB) surgery and gut hormone-based treatments are known to reduce body weight, but their effects on hypothalamic gene expression and signaling pathways are poorly studied. Metho...

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Detalles Bibliográficos
Autores principales: Dischinger, Ulrich, Heckel, Tobias, Bischler, Thorsten, Hasinger, Julia, Königsrainer, Malina, Schmitt-Böhrer, Angelika, Otto, Christoph, Fassnacht, Martin, Seyfried, Florian, Hankir, Mohammed Khair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746874/
https://www.ncbi.nlm.nih.gov/pubmed/35010991
http://dx.doi.org/10.3390/nu14010116