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Determination of the Peptide AWRK6 in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) and Its Application to Pharmacokinetics

AWRK6 was a synthesized peptide developed based on the natural occurring peptide dybowskin-2CDYa, which was discovered in frog skin in our previous study. Here, a quantitative determination method for AWRK6 analysis in rat plasma by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) was...

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Detalles Bibliográficos
Autores principales: Jin, Lili, Ding, Haibo, Degirmenci, Volkan, Xin, Hongchuan, Miao, Qifan, Wang, Qiuyu, Zhang, Dianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746970/
https://www.ncbi.nlm.nih.gov/pubmed/35011324
http://dx.doi.org/10.3390/molecules27010092