Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice

Transdifferentiation (or activation) of hepatic stellate cells (HSCs) to myofibroblasts is a key event in liver fibrosis. Activated HSCs in the tumor microenvironment reportedly promote tumor progression. This study analyzed the effect of an inhibitor of HSC activation, retinol-binding protein–album...

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Detalles Bibliográficos
Autores principales: Kang, Min-Jung, Lee, Soovin, Jung, Usuk, Mandal, Chanchal, Park, Heekyung, Stetler-Stevenson, William G., Kim, Young-Sik, Moon, Ji Wook, Park, Sun-Hwa, Oh, Junseo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747013/
https://www.ncbi.nlm.nih.gov/pubmed/34428424
http://dx.doi.org/10.1016/j.ajpath.2021.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747013/
https://www.ncbi.nlm.nih.gov/pubmed/34428424
http://dx.doi.org/10.1016/j.ajpath.2021.08.004

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