Sesquiterpene Lactones with Dual Inhibitory Activity against the Trypanosoma brucei Pteridine Reductase 1 and Dihydrofolate Reductase

The parasite Trypanosoma brucei (T. brucei) is responsible for human African trypanosomiasis (HAT) and the cattle disease “Nagana” which to this day cause severe medical and socio-economic issues for the affected areas in Africa. So far, most of the available treatment options are accompanied by har...

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Detalles Bibliográficos
Autores principales: Possart, Katharina, Herrmann, Fabian C., Jose, Joachim, Costi, Maria P., Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747069/
https://www.ncbi.nlm.nih.gov/pubmed/35011381
http://dx.doi.org/10.3390/molecules27010149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747069/
https://www.ncbi.nlm.nih.gov/pubmed/35011381
http://dx.doi.org/10.3390/molecules27010149

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