Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice

Folate and choline are interconnected metabolically. The MTHFD1 R653Q SNP is a risk factor for birth defects and there are concerns that choline deficiency may interact with this SNP and exacerbate health risks. 80–90% of women do not meet the Adequate Intake (AI) for choline. The objective of this...

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Detalles Bibliográficos
Autores principales: Christensen, Karen E., Malysheva, Olga V., Carlin, Stephanie, Matias, Fernando, MacFarlane, Amanda J., Jacobs, René L., Caudill, Marie A., Rozen, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747146/
https://www.ncbi.nlm.nih.gov/pubmed/35011003
http://dx.doi.org/10.3390/nu14010127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747146/
https://www.ncbi.nlm.nih.gov/pubmed/35011003
http://dx.doi.org/10.3390/nu14010127

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