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Development and Evaluation of 2-Amino-7-Fluorophenazine 5,10-Dioxide Polymeric Micelles as Antitumoral Agents for 4T1 Breast Cancer

2-Amino-7-fluorophenazine 5,10-dioxide (FNZ) is a bioreducible prodrug, poorly soluble in water, with potential anticancer activity on hypoxic-tumors. This poor solubility limits its potential applications in clinic. Amphiphilic pristine polymeric micelles (PMs) based on triblock copolymers Pluronic...

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Detalles Bibliográficos
Autores principales: Lecot, Nicole, Dávila, Belén, Sánchez, Carina, Fernández, Marcelo, González, Mercedes, Cabral, Pablo, Cerecetto, Hugo, Glisoni, Romina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747360/
https://www.ncbi.nlm.nih.gov/pubmed/35012094
http://dx.doi.org/10.3390/polym14010071