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Nano-scale architecture of blood-brain barrier tight-junctions

Tight junctions (TJs) between blood-brain barrier (BBB) endothelial cells construct a robust physical barrier, whose damage underlies BBB dysfunctions related to several neurodegenerative diseases. What makes these highly specialized BBB-TJs extremely restrictive remains unknown. Here, we use super-...

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Detalles Bibliográficos
Autores principales: Sasson, Esther, Anzi, Shira, Bell, Batia, Yakovian, Oren, Zorsky, Meshi, Deutsch, Urban, Engelhardt, Britta, Sherman, Eilon, Vatine, Gad, Dzikowski, Ron, Ben-Zvi, Ayal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747500/
https://www.ncbi.nlm.nih.gov/pubmed/34951586
http://dx.doi.org/10.7554/eLife.63253