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Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Different melanoma subtypes exhibit specific and non-overlapping sets of oncogene and tumor suppressor mutations, despite a common cell of origin in melanocytes. For example, activation of the Gα(q/11) signaling pathway is a characteristic initiating event in primary melanomas that arise in the derm...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747508/ https://www.ncbi.nlm.nih.gov/pubmed/34939927 http://dx.doi.org/10.7554/eLife.71825 |