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Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria

Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of animal models remains a challenge. Here, we use comparative transcriptomics of blood to evaluate the systemic host response and its concordance...

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Detalles Bibliográficos
Autores principales: Georgiadou, Athina, Dunican, Claire, Soro-Barrio, Pablo, Lee, Hyun Jae, Kaforou, Myrsini, Cunnington, Aubrey J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747512/
https://www.ncbi.nlm.nih.gov/pubmed/35006075
http://dx.doi.org/10.7554/eLife.70763