Rapid genome editing by CRISPR-Cas9-POLD3 fusion

Precision CRISPR gene editing relies on the cellular homology-directed DNA repair (HDR) to introduce custom DNA sequences to target sites. The HDR editing efficiency varies between cell types and genomic sites, and the sources of this variation are incompletely understood. Here, we have studied the...

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Detalles Bibliográficos
Autores principales: Reint, Ganna, Li, Zhuokun, Labun, Kornel, Keskitalo, Salla, Soppa, Inkeri, Mamia, Katariina, Tolo, Eero, Szymanska, Monika, Meza-Zepeda, Leonardo A, Lorenz, Susanne, Cieslar-Pobuda, Artur, Hu, Xian, Bordin, Diana L, Staerk, Judith, Valen, Eivind, Schmierer, Bernhard, Varjosalo, Markku, Taipale, Jussi, Haapaniemi, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747517/
https://www.ncbi.nlm.nih.gov/pubmed/34898428
http://dx.doi.org/10.7554/eLife.75415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747517/
https://www.ncbi.nlm.nih.gov/pubmed/34898428
http://dx.doi.org/10.7554/eLife.75415

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