Inhibition of CXCR4 in Spinal Cord and DRG with AMD3100 Attenuates Colon-Bladder Cross-Organ Sensitization

BACKGROUND: Cross-sensitization of pelvic organs is one theory for why symptoms of gut sickness and interstitial cystitis/bladder pain syndrome overlap. Experimental colitis has been shown to trigger bladder hyperactivity and hyperalgesia in rats. The chemokine receptor CXCR4 plays a key role in bla...

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Detalles Bibliográficos
Autores principales: Zhang, Hengshuai, Dong, Xingyou, Yang, Zhenxing, Zhao, Jiang, Lu, Qudong, Zhu, Jingzhen, Li, Longkun, Yi, Shanhong, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747645/
https://www.ncbi.nlm.nih.gov/pubmed/35023903
http://dx.doi.org/10.2147/DDDT.S336242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747645/
https://www.ncbi.nlm.nih.gov/pubmed/35023903
http://dx.doi.org/10.2147/DDDT.S336242

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