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Combination treatment optimization using a pan-cancer pathway model

The design of efficient combination therapies is a difficult key challenge in the treatment of complex diseases such as cancers. The large heterogeneity of cancers and the large number of available drugs renders exhaustive in vivo or even in vitro investigation of possible treatments impractical. In...

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Detalles Bibliográficos
Autores principales: Schmucker, Robin, Farina, Gabriele, Faeder, James, Fröhlich, Fabian, Saglam, Ali Sinan, Sandholm, Tuomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747684/
https://www.ncbi.nlm.nih.gov/pubmed/34962919
http://dx.doi.org/10.1371/journal.pcbi.1009689