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Combination treatment optimization using a pan-cancer pathway model
The design of efficient combination therapies is a difficult key challenge in the treatment of complex diseases such as cancers. The large heterogeneity of cancers and the large number of available drugs renders exhaustive in vivo or even in vitro investigation of possible treatments impractical. In...
Autores principales: | Schmucker, Robin, Farina, Gabriele, Faeder, James, Fröhlich, Fabian, Saglam, Ali Sinan, Sandholm, Tuomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8747684/ https://www.ncbi.nlm.nih.gov/pubmed/34962919 http://dx.doi.org/10.1371/journal.pcbi.1009689 |
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