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Merkel cell polyomavirus–negative Merkel cell carcinoma is associated with JAK‐STAT and MEK‐ERK pathway activation

Merkel cell polyomavirus (MCPyV) is monoclonally integrated into the genomes of approximately 80% of Merkel cell carcinomas (MCCs). While the presence of MCPyV affects the clinicopathological features of MCC, the molecular mechanisms of MCC pathogenesis after MCPyV infection are unclear. This study...

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Detalles Bibliográficos
Autores principales: Iwasaki, Takeshi, Hayashi, Kazuhiko, Matsushita, Michiko, Nonaka, Daisuke, Kohashi, Kenichi, Kuwamoto, Satoshi, Umekita, Yoshihisa, Oda, Yoshinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748213/
https://www.ncbi.nlm.nih.gov/pubmed/34724284
http://dx.doi.org/10.1111/cas.15187