CDK1/FBXW7 facilitates degradation and ubiquitination of MLST8 to inhibit progression of renal cell carcinoma

Recent studies have reported that MLST8 is upregulated in many malignant tumors. Nevertheless, the underlying molecular mechanism is still unclear. The aim of this work was to investigate how MLST8 contributes to the development and progression of clear cell renal cell carcinoma (ccRCC). MLST8 is an...

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Detalles Bibliográficos
Autores principales: Zhang, Encheng, Chen, Siteng, Tang, Heting, Fei, Cheng, Yuan, Zhihao, Mu, Xingyu, Qin, Yan, Liu, Haixia, Fan, Yu, Tan, Mingyue, Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748215/
https://www.ncbi.nlm.nih.gov/pubmed/34741373
http://dx.doi.org/10.1111/cas.15188