Cargando…

CDK1/FBXW7 facilitates degradation and ubiquitination of MLST8 to inhibit progression of renal cell carcinoma

Recent studies have reported that MLST8 is upregulated in many malignant tumors. Nevertheless, the underlying molecular mechanism is still unclear. The aim of this work was to investigate how MLST8 contributes to the development and progression of clear cell renal cell carcinoma (ccRCC). MLST8 is an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Encheng, Chen, Siteng, Tang, Heting, Fei, Cheng, Yuan, Zhihao, Mu, Xingyu, Qin, Yan, Liu, Haixia, Fan, Yu, Tan, Mingyue, Wang, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748215/ https://www.ncbi.nlm.nih.gov/pubmed/34741373 http://dx.doi.org/10.1111/cas.15188

Ejemplares similares

FBXW7 E3 ubiquitin ligase: degrading, not degrading, or being degraded
por: Lan, Huiyin, et al.
Publicado: (2019)

The anti‐angiogenesis role of FBXW7 in diabetic retinopathy by facilitating the ubiquitination degradation of c‐Myc to orchestrate the HDAC2
por: Hu, Lihua, et al.
Publicado: (2020)

uc.77- Downregulation Promotes Colorectal Cancer Cell Proliferation by Inhibiting FBXW8-Mediated CDK4 Protein Degradation
por: Zheng, Zhijian, et al.
Publicado: (2021)

Both Ubiquitin Ligases FBXW8 and PARK2 Are Sequestrated into Insolubility by ATXN2 PolyQ Expansions, but Only FBXW8 Expression Is Dysregulated
por: Halbach, Melanie Vanessa, et al.
Publicado: (2015)

Cuproptosis-Related Genes Are Associated with Cell Cycle and Serve as the Prognostic Signature for Clear Cell Renal Cell Carcinoma
por: Guo, Tuanjie, et al.
Publicado: (2022)

Lactic Acid Metabolism and Transporter Related Three Genes Predict the Prognosis of Patients with Clear Cell Renal Cell Carcinoma
por: Guo, Tuanjie, et al.
Publicado: (2022)

FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death
por: Li, Duan-Zhuo, et al.
Publicado: (2017)

Regulation of SOX10 stability via ubiquitination-mediated degradation by Fbxw7α modulates melanoma cell migration
por: Lv, Xiao-Bin, et al.
Publicado: (2015)

The Dual Role of USP11 in Cancer
por: Guo, Tuanjie, et al.
Publicado: (2022)

Histone demethylase KDM4B contributes to advanced clear cell renal carcinoma and association with copy number variations and cell cycle progression
por: Tang, Heting, et al.
Publicado: (2023)

FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A
por: Wang, Xing, et al.
Publicado: (2022)

An OBSL1-Cul7(Fbxw8) Ubiquitin Ligase Signaling Mechanism Regulates Golgi Morphology and Dendrite Patterning
por: Litterman, Nadia, et al.
Publicado: (2011)

FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system
por: Yalla, K, et al.
Publicado: (2018)

A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
por: Okabe, Hiroshi, et al.
Publicado: (2006)

S8.5c MLST genotyping and phylogenetics of AD-hybrids
por: Cogliati, Massimo, et al.
Publicado: (2022)

MentaLiST – A fast MLST caller for large MLST schemes
por: Feijao, Pedro, et al.
Publicado: (2018)

FBXW24 controls female meiotic prophase progression by regulating SYCP3 ubiquitination
por: Wang, Yang, et al.
Publicado: (2022)

Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis
por: Qin, Mengyao, et al.
Publicado: (2022)

SCF(Fbxw5) targets kinesin‐13 proteins to facilitate ciliogenesis
por: Schweiggert, Jörg, et al.
Publicado: (2021)

FBXO9 Mediates the Cancer-Promoting Effects of ZNF143 by Degrading FBXW7 and Facilitates Drug Resistance in Hepatocellular Carcinoma
por: Wang, Zhenyu, et al.
Publicado: (2022)

mLST8 Promotes mTOR-Mediated Tumor Progression
por: Kakumoto, Kyoko, et al.
Publicado: (2015)

Correction to: S8.5c MLST genotyping and phylogenetics of AD-hybrids
Publicado: (2023)

A Novel m(6)A Gene Signature Associated With Regulatory Immune Function for Prognosis Prediction in Clear-Cell Renal Cell Carcinoma
por: Chen, Siteng, et al.
Publicado: (2021)

Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease
por: Hua, Jingsheng, et al.
Publicado: (2016)

Integrative analysis of ferroptosis regulators for clinical prognosis based on deep learning and potential chemotherapy sensitivity of prostate cancer
por: Guo, Tuanjie, et al.
Publicado: (2023)

A novel ferroptosis-related gene signature associated with cell cycle for prognosis prediction in patients with clear cell renal cell carcinoma
por: Chen, Siteng, et al.
Publicado: (2022)

ENKUR recruits FBXW7 to ubiquitinate and degrade MYH9 and further suppress MYH9‐induced deubiquitination of β‐catenin to block gastric cancer metastasis
por: Liu, Jiahao, et al.
Publicado: (2022)

Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma
por: Kurashige, J, et al.
Publicado: (2012)

Machine learning-based prognosis signature for survival prediction of patients with clear cell renal cell carcinoma
por: Chen, Siteng, et al.
Publicado: (2022)

Robust Prediction of Prognosis and Immunotherapeutic Response for Clear Cell Renal Cell Carcinoma Through Deep Learning Algorithm
por: Chen, Siteng, et al.
Publicado: (2022)

FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation
por: Yang, Fei, et al.
Publicado: (2019)

The SCF–FBXW7 E3 ubiquitin ligase triggers degradation of histone 3 lysine 4 methyltransferase complex component WDR5 to prevent mitotic slippage
por: Hänle-Kreidler, Simon, et al.
Publicado: (2022)

FBXW7-mediated ERK3 degradation regulates the proliferation of lung cancer cells
por: An, Hyun-Jung, et al.
Publicado: (2022)

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
por: Lu, Ake T., et al.
Publicado: (2016)

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Zhu, Ting, et al.
Publicado: (2021)

MLVA and MLST typing of Brucella from Qinghai, China
por: Ma, Jun-Ying, et al.
Publicado: (2016)

Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders
por: Steinebach, Christian, et al.
Publicado: (2020)

CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9
por: Zhang, Yanli, et al.
Publicado: (2021)

Chondroprotective effects of CDK4/6 inhibition via enhanced ubiquitin-dependent degradation of JUN in synovial fibroblasts
por: Hosoya, Tadashi, et al.
Publicado: (2021)

Serotyping, MLST, and Core Genome MLST Analysis of Salmonella enterica From Different Sources in China During 2004–2019
por: Yan, Shigan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oblipfpfmhu5bhjlh7ed54salv