Ferroptosis resistance determines high susceptibility of murine A/J strain to iron‐induced renal carcinogenesis

Cancer susceptibility is a critical factor in the understanding of carcinogenesis. Intraperitoneal (i.p.) injection of an iron chelate, ferric nitrilotriacetate (Fe‐NTA), produces hydroxyl radicals via Fenton reaction to induce ferroptosis in renal proximal tubules. Rats or mice subjected to repeate...

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Detalles Bibliográficos
Autores principales: Cheng, Zhen, Akatsuka, Shinya, Li, Guang Hua, Mori, Kiyoshi, Takahashi, Takashi, Toyokuni, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748236/
https://www.ncbi.nlm.nih.gov/pubmed/34699654
http://dx.doi.org/10.1111/cas.15175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748236/
https://www.ncbi.nlm.nih.gov/pubmed/34699654
http://dx.doi.org/10.1111/cas.15175

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