Stemness and immune evasion conferred by the TDO2‐AHR pathway are associated with liver metastasis of colon cancer

The aryl hydrocarbon receptor (AHR) pathway modulates the immune system in response to kynurenine, an endogenous tryptophan metabolite. IDO1 and TDO2 catalyze kynurenine production, which promotes cancer progression by compromising host immunosurveillance. However, it is unclear whether the AHR acti...

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Detalles Bibliográficos
Autores principales: Miyazaki, Toshiaki, Chung, Suyoun, Sakai, Hiroaki, Ohata, Hirokazu, Obata, Yuuki, Shiokawa, Daisuke, Mizoguchi, Yukihiro, Kubo, Takashi, Ichikawa, Hitoshi, Taniguchi, Hirokazu, Aoki, Kazunori, Soga, Tomoyoshi, Nakagama, Hitoshi, Okamoto, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748246/
https://www.ncbi.nlm.nih.gov/pubmed/34714577
http://dx.doi.org/10.1111/cas.15182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748246/
https://www.ncbi.nlm.nih.gov/pubmed/34714577
http://dx.doi.org/10.1111/cas.15182

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