Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense

Organophosphorus compound pesticides (OP) are widely used in pest control and might be misused for terrorist attacks. Although acetylcholinesterase (AChE) inhibition is the predominant toxic mechanism, OP may induce pneumonia and formation of lung edema after poisoning and during clinical treatment...

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Detalles Bibliográficos
Autores principales: Tigges, Jonas, Worek, Franz, Thiermann, Horst, Wille, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748323/
https://www.ncbi.nlm.nih.gov/pubmed/34778934
http://dx.doi.org/10.1007/s00204-021-03186-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748323/
https://www.ncbi.nlm.nih.gov/pubmed/34778934
http://dx.doi.org/10.1007/s00204-021-03186-x

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