Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH

In an effort to replace, reduce and refine animal experimentation, there is an unmet need to advance current in vitro models that offer features with physiological relevance and enhanced predictivity of in vivo toxicological output. Hepatic toxicology is key following chemical, drug and nanomaterial...

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Detalles Bibliográficos
Autores principales: Kermanizadeh, Ali, Valli, Jessica, Sanchez, Katarzyna, Hutter, Simon, Pawlowska, Agnieszka, Whyte, Graeme, Moritz, Wolfgang, Stone, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748349/
https://www.ncbi.nlm.nih.gov/pubmed/34668024
http://dx.doi.org/10.1007/s00204-021-03181-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748349/
https://www.ncbi.nlm.nih.gov/pubmed/34668024
http://dx.doi.org/10.1007/s00204-021-03181-2

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