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Homologous cardiac calcium pump regulators phospholamban and sarcolipin adopt distinct oligomeric states in the membrane

Phospholamban (PLN) and Sarcolipin (SLN) are homologous membrane proteins that belong to the family of proteins that regulate the activity of the cardiac calcium pump (sarcoplasmic reticulum Ca(2+)-ATPase, SERCA). PLN and SLN share highly conserved leucine zipper motifs that control self-association...

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Detalles Bibliográficos
Autores principales: Liu, Andy Y., Aguayo-Ortiz, Rodrigo, Guerrero-Serna, Guadalupe, Wang, Nulang, Blin, Muriel G., Goldstein, Daniel R., Michel Espinoza-Fonseca, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748397/
https://www.ncbi.nlm.nih.gov/pubmed/35035790
http://dx.doi.org/10.1016/j.csbj.2021.12.031