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Endothelial-derived extracellular microRNA-92a promotes arterial stiffness by regulating phenotype changes of vascular smooth muscle cells

Endothelial dysfunction and vascular smooth muscle cell (VSMC) plasticity are critically involved in the pathogenesis of hypertension and arterial stiffness. MicroRNAs can mediate the cellular communication between vascular endothelial cells (ECs) and neighboring cells. Here, we investigated the rol...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Wu, Haoyu, Xing, Yuanming, Ye, Yulan, He, Fangzhou, Yin, Qian, Li, Yujin, Shang, Fenqing, Shyy, John Y.-J., Yuan, Zu-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748448/
https://www.ncbi.nlm.nih.gov/pubmed/35013491
http://dx.doi.org/10.1038/s41598-021-04341-1