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Redefining the role of Ca(2+)-permeable channels in photoreceptor degeneration using diltiazem
Hereditary degeneration of photoreceptors has been linked to over-activation of Ca(2+)-permeable channels, excessive Ca(2+)-influx, and downstream activation of Ca(2+)-dependent calpain-type proteases. Unfortunately, after more than 20 years of pertinent research, unequivocal evidence proving signif...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748460/ https://www.ncbi.nlm.nih.gov/pubmed/35013127 http://dx.doi.org/10.1038/s41419-021-04482-1 |