Integrating gene expression and clinical data to identify drug repurposing candidates for hyperlipidemia and hypertension

Discovering novel uses for existing drugs, through drug repurposing, can reduce the time, costs, and risk of failure associated with new drug development. However, prioritizing drug repurposing candidates for downstream studies remains challenging. Here, we present a high-throughput approach to iden...

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Detalles Bibliográficos
Autores principales: Wu, Patrick, Feng, QiPing, Kerchberger, Vern Eric, Nelson, Scott D., Chen, Qingxia, Li, Bingshan, Edwards, Todd L., Cox, Nancy J., Phillips, Elizabeth J., Stein, C. Michael, Roden, Dan M., Denny, Joshua C., Wei, Wei-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748496/
https://www.ncbi.nlm.nih.gov/pubmed/35013250
http://dx.doi.org/10.1038/s41467-021-27751-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748496/
https://www.ncbi.nlm.nih.gov/pubmed/35013250
http://dx.doi.org/10.1038/s41467-021-27751-1

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