Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan

Aging is impacted by interventions across species, often converging on metabolic pathways. Transcription factors regulate longevity yet approaches for their pharmacological modulation to exert geroprotection remain sparse. We show that increased expression of the transcription factor Grainyhead 1 (G...

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Detalles Bibliográficos
Autores principales: Grigolon, Giovanna, Araldi, Elisa, Erni, Reto, Wu, Jia Yee, Thomas, Carolin, La Fortezza, Marco, Laube, Beate, Pöhlmann, Doris, Stoffel, Markus, Zarse, Kim, Carreira, Erick M., Ristow, Michael, Fischer, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748497/
https://www.ncbi.nlm.nih.gov/pubmed/35013237
http://dx.doi.org/10.1038/s41467-021-27732-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748497/
https://www.ncbi.nlm.nih.gov/pubmed/35013237
http://dx.doi.org/10.1038/s41467-021-27732-4

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