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Single-cell chromatin accessibility landscape in kidney identifies additional cell-of-origin in heterogenous papillary renal cell carcinoma

Papillary renal cell carcinoma (pRCC) is the most heterogenous renal cell carcinoma. Patient survival varies and no effective therapies for advanced pRCC exist. Histological and molecular characterization studies have highlighted the heterogeneity of pRCC tumours. Recent studies identified the proxi...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Zhang, Yang, Zhang, Bolei, Fu, Yao, Zhao, Xiaozhi, Zhang, Jing, Zuo, Ke, Xing, Yuexian, Jiang, Song, Qin, Zhaohui, Li, Erguang, Guo, Hongqian, Liu, Zhihong, Yang, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748507/
https://www.ncbi.nlm.nih.gov/pubmed/35013217
http://dx.doi.org/10.1038/s41467-021-27660-3