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The efficacy of PI3Kγ and EGFR inhibitors on the suppression of the characteristics of cancer stem cells

Cancer stem cells (CSCs) are capable of continuous proliferation, self-renewal and are proposed to play significant roles in oncogenesis, tumor growth, metastasis and cancer recurrence. We have established a model of CSCs that was originally developed from mouse induced pluripotent stem cells (miPSC...

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Detalles Bibliográficos
Autores principales: Xu, Yanning, Afify, Said M., Du, Juan, Liu, Bingbing, Hassan, Ghmkin, Wang, Qing, Li, Hanbo, Liu, Yixin, Fu, Xiaoying, Zhu, Zhengmao, Chen, Ling, Seno, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748513/
https://www.ncbi.nlm.nih.gov/pubmed/35013447
http://dx.doi.org/10.1038/s41598-021-04265-w