Cargando…

Metformin protects lens epithelial cells against senescence in a naturally aged mouse model

The senescence of lens epithelial cells (LECs) is a major factor leading to age-related cataract (ARC). ARC results in visual impairment and severe vision loss in elderly patients. However, the specific mechanism of ARC remains unclear, and there are no effective therapeutic agents to halt the forma...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Mengmeng, Fu, Yushan, Wang, Xu, Wu, Ruitong, Su, Dongmei, Zhou, Nan, Qi, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748516/
https://www.ncbi.nlm.nih.gov/pubmed/35013152
http://dx.doi.org/10.1038/s41420-021-00800-w