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Knockdown of NRMT enhances sensitivity of retinoblastoma cells to cisplatin through upregulation of the CENPA/Myc/Bcl2 axis

Chemotherapy resistance of tumor cells causes failure in anti-tumor therapies. Recently, N-terminal regulator of chromatin condensation 1 methyltransferase (NRMT) is abnormally expressed in different cancers. Hence, we speculate that NRMT may pay a crucial role in the development of chemosensitivity...

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Detalles Bibliográficos
Autores principales: Li, Zhongrui, Zhang, Lan, Liu, Dongrui, Yang, Zhanghui, Xuan, Di, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748520/
https://www.ncbi.nlm.nih.gov/pubmed/35013138
http://dx.doi.org/10.1038/s41420-021-00622-w