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Accuracy of mutational signature software on correlated signatures

Mutational signatures are characteristic patterns of mutations generated by exogenous mutagens or by endogenous mutational processes. Mutational signatures are important for research into DNA damage and repair, aging, cancer biology, genetic toxicology, and epidemiology. Unsupervised learning can in...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Chua, Ellora Hui Zhen, Ng, Alvin Wei Tian, Boot, Arnoud, Rozen, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748538/
https://www.ncbi.nlm.nih.gov/pubmed/35013428
http://dx.doi.org/10.1038/s41598-021-04207-6