Missense variants in the TNFA epitopes and their effects on interaction with therapeutic antibodies—in silico analysis

BACKGROUND: Tumor necrosis factor alpha (TNFA) is an important cytokine that influences multiple biological processes. It is one of the key mediators of acute and chronic systemic inflammatory reactions and plays a central role in several autoimmune diseases. A number of approved monoclonal antibodi...

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Detalles Bibliográficos
Autores principales: Ahsan, Tamim, Sajib, Abu Ashfaqur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748575/
https://www.ncbi.nlm.nih.gov/pubmed/35006391
http://dx.doi.org/10.1186/s43141-021-00288-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748575/
https://www.ncbi.nlm.nih.gov/pubmed/35006391
http://dx.doi.org/10.1186/s43141-021-00288-y

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