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Impairment of μ-calpain activation by rhTNFR:Fc reduces severe burn-induced membrane disruption in the heart

Stress cardiomyopathy is a major clinical complication after severe burn. Multiple upstream initiators have been identified; however, the downstream targets are not fully understood. This study assessed the role of the plasma membrane in this process and its relationship with the protease μ-calpain...

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Detalles Bibliográficos
Autores principales: Cao, Meng-Shu, Zhao, Ting-Yan, Song, Zhi-Long, Lu, Hong-Ting, Zheng, Yun, Gu, Xiao-Ming, Lu, Tao, Wang, Qiong, Zhou, Jing-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748603/
https://www.ncbi.nlm.nih.gov/pubmed/35013173
http://dx.doi.org/10.1038/s41420-021-00810-8