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Impairment of μ-calpain activation by rhTNFR:Fc reduces severe burn-induced membrane disruption in the heart
Stress cardiomyopathy is a major clinical complication after severe burn. Multiple upstream initiators have been identified; however, the downstream targets are not fully understood. This study assessed the role of the plasma membrane in this process and its relationship with the protease μ-calpain...
Autores principales: | Cao, Meng-Shu, Zhao, Ting-Yan, Song, Zhi-Long, Lu, Hong-Ting, Zheng, Yun, Gu, Xiao-Ming, Lu, Tao, Wang, Qiong, Zhou, Jing-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748603/ https://www.ncbi.nlm.nih.gov/pubmed/35013173 http://dx.doi.org/10.1038/s41420-021-00810-8 |
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