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Maximizing response to intratumoral immunotherapy in mice by tuning local retention
Direct injection of therapies into tumors has emerged as an administration route capable of achieving high local drug exposure and strong anti-tumor response. A diverse array of immune agonists ranging in size and target are under development as local immunotherapies. However, due to the relatively...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748612/ https://www.ncbi.nlm.nih.gov/pubmed/35013154 http://dx.doi.org/10.1038/s41467-021-27390-6 |