Cargando…

A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues

Proteolysis-targeting chimaeras (PROTACs) as well as molecular glues such as immunomodulatory drugs (IMiDs) and indisulam are drugs that induce interactions between substrate proteins and an E3 ubiquitin ligases for targeted protein degradation. Here, we develop a workflow based on proximity-depende...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamanaka, Satoshi, Horiuchi, Yuto, Matsuoka, Saya, Kido, Kohki, Nishino, Kohei, Maeno, Mayaka, Shibata, Norio, Kosako, Hidetaka, Sawasaki, Tatsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748630/ https://www.ncbi.nlm.nih.gov/pubmed/35013300 http://dx.doi.org/10.1038/s41467-021-27818-z

Ejemplares similares

AirID, a novel proximity biotinylation enzyme, for analysis of protein–protein interactions
por: Kido, Kohki, et al.
Publicado: (2020)

An IMiD-induced SALL4 degron system for selective degradation of target proteins
por: Yamanaka, Satoshi, et al.
Publicado: (2020)

Biotinylated-sortase self-cleavage purification (BISOP) method for cell-free produced proteins
por: Matsunaga, Satoko, et al.
Publicado: (2010)

Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation
por: Yamanaka, Satoshi, et al.
Publicado: (2023)

E3 ligase ligand optimization of Clinical PROTACs
por: Jiang, Hanrui, et al.
Publicado: (2023)

CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis
por: Sugiyama, Shusei, et al.
Publicado: (2022)

Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase
por: Rana, Sandeep, et al.
Publicado: (2021)

Simple Screening Method for Autoantigen Proteins Using the N-Terminal Biotinylated Protein Library Produced by Wheat Cell-Free Synthesis
por: Matsuoka, Kazuhiro, et al.
Publicado: (2010)

Enantioselective Benzylation and Allylation of α-Trifluoromethoxy Indanones under Phase-Transfer Catalysis
por: Liang, Yumeng, et al.
Publicado: (2019)

Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase
por: Smith, Blake E., et al.
Publicado: (2019)

Extracellular calcium functions as a molecular glue for transmembrane helices to activate the scramblase Xkr4
por: Zhang, Panpan, et al.
Publicado: (2023)

PROTAC-DB: an online database of PROTACs
por: Weng, Gaoqi, et al.
Publicado: (2020)

Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs
por: Zheng, Shuhua, et al.
Publicado: (2020)

E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points
por: Bricelj, Aleša, et al.
Publicado: (2021)

Force Dependent Biotinylation of Myosin IIA by α-Catenin Tagged with a Promiscuous Biotin Ligase
por: Ueda, Shuji, et al.
Publicado: (2015)

DNA Modifications Enabling Proximity Biotinylation
por: Wilbanks, Brandon, et al.
Publicado: (2023)

In vivo target protein degradation induced by PROTACs based on E3 ligase DCAF15
por: Li, Liang, et al.
Publicado: (2020)

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs
por: Girardini, Miriam, et al.
Publicado: (2019)

E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones
por: Ishida, Tasuku, et al.
Publicado: (2020)

Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs
por: Negi, Arvind, et al.
Publicado: (2022)

PROTAC-DB 2.0: an updated database of PROTACs
por: Weng, Gaoqi, et al.
Publicado: (2022)

Proteasomal Degradation of Zn-Dependent Hdacs: The E3-Ligases Implicated and the Designed Protacs That Enable Degradation
por: Márquez-Cantudo, Laura, et al.
Publicado: (2021)

A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors
por: Takahashi, Hirotaka, et al.
Publicado: (2020)

Proximity Utilizing Biotinylation of Nuclear Proteins in vivo
por: Kulyyassov, Arman, et al.
Publicado: (2015)

Off-the-shelf proximity biotinylation for interaction proteomics
por: Santos-Barriopedro, Irene, et al.
Publicado: (2021)

Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation
por: Maniaci, Chiara, et al.
Publicado: (2017)

Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs
por: Bai, Nan, et al.
Publicado: (2022)

Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope
por: Ma, Sinan, et al.
Publicado: (2022)

Biotinylation by antibody recognition - A method for proximity labeling
por: Bar, Daniel Z, et al.
Publicado: (2017)

Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
por: Naito, Mikihiko, et al.
Publicado: (2019)

PROTACs in gastrointestinal cancers
por: Chen, Yu, et al.
Publicado: (2022)

DeepPROTACs is a deep learning-based targeted degradation predictor for PROTACs
por: Li, Fenglei, et al.
Publicado: (2022)

Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders
por: Diehl, Claudia J., et al.
Publicado: (2022)

Screening of Proximal and Interacting Proteins in Rice Protoplasts by Proximity-Dependent Biotinylation
por: Lin, Qiupeng, et al.
Publicado: (2017)

In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation
por: Lin, Xianzhi, et al.
Publicado: (2021)

Self-disproportionation of enantiomers of thalidomide and its fluorinated analogue via gravity-driven achiral chromatography: mechanistic rationale and implications
por: Maeno, Mayaka, et al.
Publicado: (2015)

CP5 system, for simple and highly efficient protein purification with a C-terminal designed mini tag
por: Takeda, Hiroyuki, et al.
Publicado: (2017)

Biotinylated Cyclooligosaccharides for Paclitaxel Solubilization
por: Cho, Eunae, et al.
Publicado: (2018)

Streptavidin Coverage on Biotinylated Surfaces
por: Hamming, P. H. Erik, et al.
Publicado: (2021)

In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation
por: Gillingham, Alison K, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ebe62iljpp4tkl4eta8lroe6lv