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Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity

Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-tumoral heterogeneity implicated in treatment resistance and progression. While regional and single cell transcriptomic variations of glioblastoma have been recently resolved, downstream phenotype-level proteo...

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Detalles Bibliográficos
Autores principales: Lam, K. H. Brian, Leon, Alberto J., Hui, Weili, Lee, Sandy Che-Eun, Batruch, Ihor, Faust, Kevin, Klekner, Almos, Hutóczki, Gábor, Koritzinsky, Marianne, Richer, Maxime, Djuric, Ugljesa, Diamandis, Phedias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748638/
https://www.ncbi.nlm.nih.gov/pubmed/35013227
http://dx.doi.org/10.1038/s41467-021-27667-w