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Canagliflozin protects against cisplatin-induced acute kidney injury by AMPK-mediated autophagy in renal proximal tubular cells

Sodium-glucose cotransporter 2 inhibitors, which are recently introduced as glucose-lowering agents, improve cardiovascular and renal outcomes in patients with diabetes mellitus. These drugs also have beneficial effects in various kidney disease models. However, the effect of SGLT2 inhibitors on cis...

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Detalles Bibliográficos
Autores principales: Park, Cheol Ho, Lee, Bin, Han, Myeonggil, Rhee, Woo Joong, Kwak, Man Sup, Yoo, Tae-Hyun, Shin, Jeon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748642/
https://www.ncbi.nlm.nih.gov/pubmed/35013111
http://dx.doi.org/10.1038/s41420-021-00801-9