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Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF

Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze various oxidative biotransformations. Due to their catalytic flexibility and high efficiency, Fe/αKG oxygenases have attracted keen attention for their application as biocatalysts. Here, we report the biochemical and structural...

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Detalles Bibliográficos
Autores principales: Tao, Hui, Mori, Takahiro, Chen, Heping, Lyu, Shuang, Nonoyama, Akihito, Lee, Shoukou, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748661/
https://www.ncbi.nlm.nih.gov/pubmed/35013177
http://dx.doi.org/10.1038/s41467-021-27636-3