Cargando…
Molecular insights into the unusually promiscuous and catalytically versatile Fe(II)/α-ketoglutarate-dependent oxygenase SptF
Non-heme iron and α-ketoglutarate-dependent (Fe/αKG) oxygenases catalyze various oxidative biotransformations. Due to their catalytic flexibility and high efficiency, Fe/αKG oxygenases have attracted keen attention for their application as biocatalysts. Here, we report the biochemical and structural...
Autores principales: | Tao, Hui, Mori, Takahiro, Chen, Heping, Lyu, Shuang, Nonoyama, Akihito, Lee, Shoukou, Abe, Ikuro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748661/ https://www.ncbi.nlm.nih.gov/pubmed/35013177 http://dx.doi.org/10.1038/s41467-021-27636-3 |
Ejemplares similares
-
Structural basis for endoperoxide-forming oxygenases
por: Mori, Takahiro, et al.
Publicado: (2022) -
Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI
por: Mori, Takahiro, et al.
Publicado: (2021) -
SERIneALanine Killer: SPT promiscuity inhibits tumour growth via intra-tumoral deoxysphingolipid production
por: Falcone, Mattia, et al.
Publicado: (2020) -
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis
por: Nakashima, Yu, et al.
Publicado: (2018) -
A Measure of the Promiscuity of Proteins and Characteristics of Residues in the Vicinity of the Catalytic Site That Regulate Promiscuity
por: Chakraborty, Sandeep, et al.
Publicado: (2012)