[(13)C]bicarbonate labelled from hyperpolarized [1-(13)C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state

Hyperpolarized [1-(13)C]pyruvate enables direct in vivo assessment of real-time liver enzymatic activities by (13)C magnetic resonance. However, the technique usually requires the injection of a highly supraphysiological dose of pyruvate. We herein demonstrate that liver metabolism can be measured i...

Descripción completa

Detalles Bibliográficos
Autores principales: Can, Emine, Bastiaansen, Jessica A. M., Couturier, Dominique-Laurent, Gruetter, Rolf, Yoshihara, Hikari A. I., Comment, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748681/
https://www.ncbi.nlm.nih.gov/pubmed/35013537
http://dx.doi.org/10.1038/s42003-021-02978-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748681/
https://www.ncbi.nlm.nih.gov/pubmed/35013537
http://dx.doi.org/10.1038/s42003-021-02978-2

Ejemplares similares