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[(13)C]bicarbonate labelled from hyperpolarized [1-(13)C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state

Hyperpolarized [1-(13)C]pyruvate enables direct in vivo assessment of real-time liver enzymatic activities by (13)C magnetic resonance. However, the technique usually requires the injection of a highly supraphysiological dose of pyruvate. We herein demonstrate that liver metabolism can be measured i...

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Detalles Bibliográficos
Autores principales:	Can, Emine, Bastiaansen, Jessica A. M., Couturier, Dominique-Laurent, Gruetter, Rolf, Yoshihara, Hikari A. I., Comment, Arnaud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748681/ https://www.ncbi.nlm.nih.gov/pubmed/35013537 http://dx.doi.org/10.1038/s42003-021-02978-2

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