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METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA

N6-methyladenosine (m6A) is one of the most important epigenetic regulation of RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic cardiomyopathy (DCM) is very limited. In this study, we sought to define the role of METTL14-mediated m6A modification in pyroptosis a...

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Detalles Bibliográficos
Autores principales: Meng, Liping, Lin, Hui, Huang, Xingxiao, Weng, Jingfan, Peng, Fang, Wu, Shengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748685/
https://www.ncbi.nlm.nih.gov/pubmed/35013106
http://dx.doi.org/10.1038/s41419-021-04484-z