Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association

Owing to a lack of response to the anti-PD1 therapy for most cancer patients, we develop a network approach to infer genes, pathways, and potential therapeutic combinations that are associated with tumor response to anti-PD1. Here, our prediction identifies genes and pathways known to be associated...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Chin, Wang, Y. Alan, Livingston, J. Andrew, Zhang, Jianhua, Futreal, P. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748689/
https://www.ncbi.nlm.nih.gov/pubmed/35013211
http://dx.doi.org/10.1038/s41467-021-27651-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748689/
https://www.ncbi.nlm.nih.gov/pubmed/35013211
http://dx.doi.org/10.1038/s41467-021-27651-4

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