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Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association
Owing to a lack of response to the anti-PD1 therapy for most cancer patients, we develop a network approach to infer genes, pathways, and potential therapeutic combinations that are associated with tumor response to anti-PD1. Here, our prediction identifies genes and pathways known to be associated...
Autores principales: | Wu, Chia-Chin, Wang, Y. Alan, Livingston, J. Andrew, Zhang, Jianhua, Futreal, P. Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748689/ https://www.ncbi.nlm.nih.gov/pubmed/35013211 http://dx.doi.org/10.1038/s41467-021-27651-4 |
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