Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding

Several studies showed that seeding of solutions of monomeric fibril proteins with ex vivo amyloid fibrils accelerated the kinetics of fibril formation in vitro but did not necessarily replicate the seed structure. In this research we use cryo-electron microscopy and other methods to analyze the abi...

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Detalles Bibliográficos
Autores principales: Heerde, Thomas, Rennegarbe, Matthies, Biedermann, Alexander, Savran, Dilan, Pfeiffer, Peter B., Hitzenberger, Manuel, Baur, Julian, Puscalau-Girtu, Ioana, Zacharias, Martin, Schwierz, Nadine, Haupt, Christian, Schmidt, Matthias, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748726/
https://www.ncbi.nlm.nih.gov/pubmed/35013242
http://dx.doi.org/10.1038/s41467-021-27688-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748726/
https://www.ncbi.nlm.nih.gov/pubmed/35013242
http://dx.doi.org/10.1038/s41467-021-27688-5

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